Boc-Gly-OH

CAS Number: 4530-20-5
Category: N-Boc Amino Acids
Synonyms: N-(tert-butoxycarbonyl)glycine
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number4530-20-5
Molecular FormulaC7H13NO4
Molecular Weight175.18
Purity99%
AppearanceWhite to off-white solid
Storage ConditionsRoom Temperature
Package100G,1KG, 25KG

Product Overview

N-(tert-butoxycarbonyl)glycine

 

Applications

  • N-Protection Strategy: The tert-butoxycarbonyl (Boc) group masks the α-amino functionality, preventing undesirable side reactions at the amino terminus during condensation reactions. It is selectively cleaved under acidolytic conditions (typically using TFA or HCl in ethyl acetate/dioxane).
  • Peptide Synthesis: Serves as an essential reactant in Boc-based solid-phase (SPPS) and solution-phase peptide synthesis for introducing flexible, achiral glycine residues into peptide chains.
  • Pharmaceutical Building Block: Applied in the synthesis of peptidomimetics, drug delivery conjugates, and bioactive molecules where a flexible link or glycine motif is required

Quality Assurance

Can be tested according to the customer’s method of analysis. Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.