tert-Butyl azetidin-3-ylcarbamate hydrochloride

CAS Number: 217806-26-3
Category: Camizestrant Intermediates
Synonyms: 3-(Boc-amino)azetidine hydrochloride, tert-butyl 3-azetidinylcarbamate hydrochloride
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number217806-26-3
Molecular FormulaC8H17ClN2O2
Molecular Weight208.69
Purity98%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
PackageFrom 100g/bottle to 25kg/drum

Product Overview

CAS 217806-26-3  tert-Butyl azetidin-3-ylcarbamate hydrochloride (also commonly known as 3-(Boc-amino)azetidine hydrochloride or tert-butyl N-(azetidin-3-yl)carbamate hydrochloride).

Applications

Four-Membered Ring Scaffold: Contains a strained 3-aminoazetidine core, which is increasingly popular in modern medicinal chemistry to impart conformational rigidity and improve solubility/pharmacokinetic profiles.

Protecting Group Strategy: Features a Boc (tert-butoxycarbonyl) protected 3-amino group, while the secondary amine in the azetidine ring is present as a free amine hydrochloride salt, enabling selective N1-alkylation, acylation, or arylation.

Medicinal Chemistry Building Block: Frequently used as an intermediate in drug discovery programs to introduce functionalized azetidine linkers or rigid aliphatic motifs into target pharmaceutical molecules.

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.