Fmoc-α-Me-Leu-OH

CAS Number: 312624-65-0
Category: N-Fmoc Amino Acids
Synonyms: (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-2,4-dimethylpentanoic acid / N-Fmoc-$\alpha$-methyl-L-leucine
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number312624-65-0
Molecular FormulaC22H25NO4
Molecular Weight367.44
Purity98%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
Package100G,1KG, 25KG

Product Overview

Fmoc-α-Me-Leu-OH | 312624-65-0

Applications

An alpha-methylated non-canonical amino acid derivative used in Solid-Phase Peptide Synthesis (SPPS). The addition of the alpha-methyl group stabilizes peptide secondary structures (such as alpha-helices) and improves metabolic stability against enzymatic degradation by proteases. It is widely used in drug discovery research, including the synthesis of peptide analogs like oxytocin receptor agonists.

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.