Fmoc-Lys(Mtt)-OH

CAS Number: 167393-62-6
Category: N-Fmoc Amino Acids
Synonyms: N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-(4-methyltrityl)-L-lysine / (2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-6-[(4-methylphenyl)-diphenylmethyl]aminohexanoic acid

Product Specifications

CAS Number167393-62-6
Molecular Formula C41H40N2O4
Molecular Weight624.78
Purity98%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
Package100G,1KG, 25KG

Product Overview

Fmoc-L-Lys(Mtt)-OH CAS: 167393-62-6

Applications

An orthogonally protected lysine derivative widely used in Solid-Phase Peptide Synthesis (SPPS). The side-chain 4-methyltrityl (Mtt) protecting group is highly acid-labile and can be selectively cleaved using mild acidic conditions (such as 1% TFA in DCM) while leaving resin linkages (e.g., Wang or Rink amide resins) and standard Fmoc/Boc groups intact. This orthogonal deprotection capability makes it an ideal building block for synthesizing cyclic peptides, branched structures, side-chain ubiquitinated/lipidated peptides, and fluorescently labeled conjugates.

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.