Fmoc-Ser(tBu)-OH
CAS Number: 71989-33-8
Category:
N-Fmoc Amino Acids
Synonyms: N-(9-Fluorenylmethoxycarbonyl)-O-tert-butyl-L-serine / (2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3-[(2-methylpropan-2-yl)oxy]propanoic acid
GMP-compliant
Commercial supply&le stock
Various Packaging Available
Factory documentation support
Product Specifications
| CAS Number | 71989-33-8 |
|---|---|
| Molecular Formula | C22H25NO5 |
| Molecular Weight | 383.44 |
| Purity | 99% |
| Appearance | White to off-white solid |
| Storage Conditions | Room Temperature |
| Package | 100G,1KG, 25KG |
Product Overview
Fmoc-Ser(tBu)-OH; Fmoc-L-Ser(tBu)-OH CAS: 71989-33-8
Applications
The standard orthogonally protected serine derivative utilized in Fmoc Solid-Phase Peptide Synthesis (SPPS). The base-labile Fmoc group on the alpha-amino group allows selective elongation of the peptide chain, while the acid-labile tert-butyl (tBu) ether protects the side-chain hydroxyl group from unwanted acylations or side reactions. The tBu group remains stable during routine Fmoc cleavage steps and is cleaved concurrently with the resin bond during final trifluoroacetic acid (TFA) treatment.
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
