Fmoc-Thr(tBu)-OH
CAS Number: 71989-35-0
Category:
N-Fmoc Amino Acids
Synonyms: N-(9-Fluorenylmethoxycarbonyl)-O-tert-butyl-L-threonine / (2S,3R)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3-[(2-methylpropan-2-yl)oxy]butanoic acid
GMP-compliant
Commercial supply&le stock
Various Packaging Available
Factory documentation support
Product Specifications
| CAS Number | 71989-35-0 |
|---|---|
| Molecular Formula | C23H27NO5 |
| Molecular Weight | 397.47 |
| Purity | 99% |
| Appearance | White to off-white solid |
| Storage Conditions | Room Temperature |
| Package | 100G,1KG, 25KG |
Product Overview
Fmoc-Thr(tBu)-OH; Fmoc-O-tert-butyl-L-threonine CAS: 71989-35-0
Applications
The standard orthogonally protected threonine derivative used in Fmoc Solid-Phase Peptide Synthesis (SPPS). The base-labile Fmoc group on the alpha-amino site allows step-by-step chain elongation, while the acid-labile tert-butyl (tBu) ether protects the side-chain secondary alcohol functionality. The tBu group remains intact during routine Fmoc cleavage steps with piperidine and is concurrently cleaved off alongside the resin bond during final trifluoroacetic acid (TFA) treatment.
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
