Fmoc-Trp(Boc)-OH

CAS Number: 143824-78-6
Category: N-Fmoc Amino Acids
Synonyms: N-(9-Fluorenylmethoxycarbonyl)-Nin-tert-butyloxycarbonyl-L-tryptophan / (2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number143824-78-6
Molecular FormulaC31H30N2O6
Molecular Weight 526.58
Purity98%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
Package100G,1KG, 25KG

Product Overview

Fmoc-Trp(Boc)-OH; Fmoc-L-Trp(Boc)-OH CAS: 143824-78-6

Applications

The standard orthogonally protected tryptophan derivative used in Fmoc Solid-Phase Peptide Synthesis (SPPS). Protecting the indole nitrogen with a Boc group prevents unwanted alkylation side reactions at the indole ring during acidic cleavage steps, drastically reducing side-product formation-especially in peptide sequences containing both tryptophan and arginine. The Boc group is cleaved concurrently with the resin linkage during final treatment with trifluoroacetic acid (TFA).

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.