Fmoc-Tyr(tBu)-OH
CAS Number: 71989-38-3
Category:
N-Fmoc Amino Acids
Synonyms: N-(9-Fluorenylmethoxycarbonyl)-O-tert-butyl-L-tyrosine / (2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
GMP-compliant
Commercial supply&le stock
Various Packaging Available
Factory documentation support
Product Specifications
| CAS Number | 71989-38-3 |
|---|---|
| Molecular Formula | C28H29NO5 |
| Molecular Weight | 459.53 |
| Purity | 99% |
| Appearance | White to off-white solid |
| Storage Conditions | Room Temperature |
| Package | 100G,1KG, 25KG |
Product Overview
Fmoc-Tyr(tBu)-OH; Fmoc-O-tert-butyl-L-tyrosine CAS: 71989-38-3
Applications
The standard orthogonally protected tyrosine derivative used in Fmoc Solid-Phase Peptide Synthesis (SPPS). Protecting the phenolic hydroxyl group with an acid-labile tert-butyl (tBu) ether prevents undesirable side reactions—such as O-acylation during coupling steps or side-chain alkylation during cleavage. The tBu group remains stable during routine Fmoc deprotection (piperidine treatment) and is removed simultaneously with resin cleavage using trifluoroacetic acid (TFA).
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
