Fmoc-Tyr(tBu)-Ser(ψ Me,Me pro)-OH
CAS Number: 878797-09-2
Category:
N-Fmoc Amino Acids
Synonyms: 4S)-3-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-L-tyrosyl]-2,2-dimethyloxazolidine-4-carboxylic acid
GMP-compliant
Commercial supply&le stock
Various Packaging Available
Factory documentation support
Product Specifications
| CAS Number | 878797-09-2 |
|---|---|
| Molecular Formula | C34H38N2O7 |
| Molecular Weight | 586.69 |
| Purity | 95% |
| Appearance | White to off-white solid |
| Storage Conditions | 2-8°C |
| Package | 100G,1KG, 25KG |
Product Overview
Fmoc-Tyr(tBu)-Ser(ψ Me,Me pro)-OH; Fmoc-Tyr(tBu)-Ser(psiMe,Mepro)-OH CAS: 878797-09-2
Applications
A specialized pseudoproline (oxazolidine) dipeptide building block widely used in Fmoc Solid-Phase Peptide Synthesis (SPPS). Pseudoproline derivatives disrupt beta-sheet secondary structure formation and backbone aggregation during peptide assembly, significantly increasing coupling efficiency, reaction rates, and yields in long or difficult peptide sequences. The oxazolidine ring is ring-opened under standard acidic TFA cleavage conditions to restore the native Tyr-Ser sequence.
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
