H-Thr(tBu)-OMe HCl

CAS Number: 71989-43-0
Category: Amino Acid Esters
Synonyms: Methyl O-(tert-butyl)-L-threoninate hydrochloride / (2S,3R)-methyl 2-amino-3-(tert-butoxy)butanoate hydrochloride
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number71989-43-0
Molecular FormulaC9H19NO3 HCl
Molecular Weight225.72
Purity98%
AppearanceWhite to off-white solid
Storage ConditionsRoom Temperature
Package100G,1KG, 25KG

Product Overview

H-Thr(tBu)-OMe·HCl; H-L-Thr(tBu)-OMe·HCl CAS: 71989-43-0

Applications

A protected threonine derivative widely used as a C-terminal building block or intermediate in peptide synthesis and liquid-phase fragment assembly. The side-chain hydroxyl group is protected as an acid-labile tert-butyl (tBu) ether, while the C-terminus is esterified as a methyl ester. The free α-amino group (as a stable hydrochloride salt) allows direct coupling to N-protected amino acids. The methyl ester can later be selectively hydrolyzed under mild alkaline conditions or converted to a peptide hydrazide for subsequent fragment condensations.

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.