N-Acetyl-L-leucine
Product Specifications
| CAS Number | 1188-21-2 |
|---|---|
| Molecular Formula | C8H15NO3 |
| Molecular Weight | 173.21 |
| Purity | ≥99.0% |
| Appearance | White to off-white solid |
| Storage Conditions | 2-8°C |
| Package | From 100g/bottle to 25kg/drum |
Product Overview
Ac-Leu-OH CAS:1188-21-2
Applications
Used as an N-terminal capping monomer in solid-phase peptide synthesis (SPPS) or solution-phase peptide synthesis (LPPS/TAPS) when the peptide sequence requires an N-acetylated terminus.
Serves as a chiral building block or chiral auxiliary in organic synthesis.
Pharmaceutical & Clinical Applications:Neurological Disorders & Vertigo: Acetyl-leucine (and specifically its enantiomer N-acetyl-L-leucine) is widely investigated and prescribed for cerebellar ataxia, lysosomal storage diseases (e.g., Niemann-Pick disease type C), and acute vertigo treatment.
Neuroprotection: Plays a role in restoring membrane potential and metabolic function in damaged vestibular/cerebellar neurons.
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
