Z-Glu-OtBu

CAS Number: 5891-45-2
Category: CBZ- Amino Acids
Synonyms: N-Carbobenzyloxy-L-glutamic acid $\alpha$-tert-butyl ester / (S)-5-(benzyloxy)-4-(((benzyloxy)carbonyl)amino)-5-oxopentanoic acid derivative (Cbz-Glu-OtBu)
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number5891-45-2
Molecular FormulaC17H23NO6
Molecular Weight337.37
Purity99%
AppearanceWhite to off-white solid
Storage ConditionsRoom Temperature
Package100G,1KG, 25KG

Product Overview

N-Carbobenzyloxy-L-glutamic acid alpha-tert-butyl ester / (S)-5-(benzyloxy)-4-(((benzyloxy)carbonyl)amino)-5-oxopentanoic acid derivative (Cbz-Glu-OtBu)

Applications

A protected glutamic acid derivative used as a key building block in liquid-phase and solid-phase peptide synthesis (SPPS). The alpha-carboxylic acid is protected as a acid-labile tert-butyl ester (OtBu), while the alpha-amino group is protected by the hydrogenolytically cleavable benzyloxycarbonyl (Z/Cbz) group, allowing selective functionalization of the gamma-side-chain carboxyl group.

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.