4-Iodo-L-phenylalanine

CAS Number: 24250-85-9
Category: Brensocatib Intermediates
Synonyms: H-Phe(4-I)-OH, p-Iodo-L-phenylalanine, (S)-2-Amino-3-(4-iodophenyl)propionic acid
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number24250-85-9
Molecular FormulaC9H10INO2
Molecular Weight291.09
Purity≥99.0%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
PackageFrom 100g/bottle to 25kg/drum

Product Overview

CAS 24250-85-9 4-Iodo-L-phenylalanine (also commonly abbreviated as H-Phe(4-I)-OH or p-Iodo-L-phenylalanine).

Applications

Unnatural Amino Acid Building Block: Used extensively in peptide synthesis, peptidomimetic design, and biological chemistry.

Cross-Coupling Reactions: The aryl iodide functionality makes it an excellent coupling partner for palladium-catalyzed reactions (such as Suzuki-Miyaura, Heck, or Sonogashira couplings) to introduce diverse functionalized aryl, alkenyl, or alkynyl side chains into peptides.

Protein Engineering & Crystallography: Frequently incorporated into proteins via genetic code expansion or non-canonical amino acid mutagenesis to alter protein structure, introduce heavy atoms for X-ray crystallographic phasing, or attach bioorthogonal probes.

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.