Boc-Phe(4-I)-NH2

CAS Number: 868694-44-4
Category: Brensocatib Intermediates
Synonyms: Boc-Phe(4-I)-NH2, Boc-4-iodo-L-phenylalaninamide, (S)-tert-butyl (1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl)carbamate
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number868694-44-4
Molecular FormulaC14H19IN2O3
Molecular Weight390.22
Purity≥99.0%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
PackageFrom 100g/bottle to 25kg/drum

Product Overview

CAS 868694-44-4  tert-Butyl [(S)-1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate (also commonly known as Boc-Phe(4-I)-NH2 or (S)-tert-butyl (1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl)carbamate).

Applications

Derivatized Amino Acid: This molecule is the C-terminal primary amide derivative of 4-iodo-L-phenylalanine, featuring an N-terminal Boc (tert-butoxycarbonyl) protecting group.

Medicinal Chemistry & Peptidomimetics: Commonly used as a protected intermediate/building block for constructing peptide sequences or peptidomimetic compounds terminated with an amide group.

Transition-Metal Coupling Partner: The aromatic iodine (aryl iodide) handle provides a functional handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, or Heck couplings) to append modified aromatic rings,alkynes, or alkenes directly onto the peptide backbone.

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.