(S)-4-(tert-Butoxycarbonyl)-1,4-oxazepane-2-carboxylic acid
Product Specifications
| CAS Number | 1273567-44-4 |
|---|---|
| Molecular Formula | C11H19NO5 |
| Molecular Weight | 245.27 |
| Purity | 98% |
| Appearance | White to off-white solid |
| Storage Conditions | 2-8°C |
| Package | From 100g/bottle to 25kg/drum |
Product Overview
CAS 1273567-44-4 (S)-4-(tert-Butoxycarbonyl)-1,4-oxazepane-2-carboxylic acid (also commonly written as (2S)-4-[(tert-butoxy)carbonyl]-1,4-oxazepane-2-carboxylic acid).
Applications
Choral Non-Natural Amino Acid Scaffold: Features a 7-membered bicyclic/heterocyclic oxazepane core with defined (S)-stereochemistry at the C2 position, offering unique conformational rigidity compared to standard linear or 5-/6-membered ring systems.
Protecting Group Design: The ring nitrogen at position 4 is orthogonally protected with a Boc (tert-butoxycarbonyl) group, while the free carboxylic acid allows direct amide coupling or derivatization.
Pharmaceutical Intermediate: Serves as a key chiral building block in drug discovery and medicinal chemistry research, most notably used as an intermediate in the synthesis of small-molecule therapeutics such as Brensocatib (a cathepsin C inhibitor).
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
