tert-Butyl (5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate
Product Specifications
| CAS Number | 1201187-44-1 |
|---|---|
| Molecular Formula | C18H20N4O4S |
| Molecular Weight | 388.44 |
| Purity | ≥99.0% |
| Appearance | White to off-white solid |
| Storage Conditions | 2-8°C |
| Package | From 100g/bottle to 25kg/drum |
Product Overview
CAS 1201187-44-1 tert-Butyl (5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate (also named tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate).
Applications
Heterocyclic Core: Features a fused pyrrolo[2,3-b]pyrazine bicyclic framework, a bioisostere to pyrrolo[2,3-b]pyridine (7-azaindole) and imidazopyrazine rings.
Protecting Group Strategy: Dual-protected building block possessing an N-Boc protecting group at the 2-amino position and a Ts (tosyl) protecting group on the pyrrole nitrogen (N5) to ensure orthogonal reactivity during cross-couplings and functional group manipulations.
Medicinal Chemistry Use: Widely utilized as an advanced intermediate in kinase inhibitor development and pharmaceutical synthesis targeting kinase signaling pathways.
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
