2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile

2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile

CAS Number: 312307-38-3
Category: Aprepitant Intermediates
Synonyms: 2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile, 2-Malononitrilyl-1-(2-fluorophenyl)ethanone
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Product Specifications

CAS Number312307-38-3
Molecular FormulaC11H7FN2O
Molecular Weight202.18
Purity≥99.0%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
PackageFrom 100g/bottle to 25kg/drum

Product Overview

2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile (CAS: 312307-38-3) is a functionalized dinitrile intermediate and organic building block.

Applications

Serves as a key starting material and intermediate in the synthesis of potassium-competitive acid blockers (P-CABs), most notably in the preparation of Vonoprazan (TAK-438) and its core pyrrole intermediates (such as 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde).

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.

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