3’,5’-Bis(Trifluoromethyl)acetophenone

3’,5’-Bis(Trifluoromethyl)acetophenone

CAS Number: 30071-93-3
Category: Aprepitant Intermediates
Synonyms: 3',5'-Bis(trifluoromethyl)acetophenone;
1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)cyclopropanecarboxylic acid, 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxylic acid
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✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number30071-93-3
Molecular FormulaC10H6F6O
Molecular Weight256.14
Purity≥99.0%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
PackageFrom 100g/bottle to 25kg/drum

Product Overview

1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid (CAS: 30071-93-3) is a functionalized organofluorine building block and key intermediate in pharmaceutical chemistry.

Applications

Serves as a vital core intermediate in the synthesis of cystic fibrosis transmembrane conductance regulator (CFTR) modulators, most notably Lumacaftor (VX-809) and Tezacaftor (VX-661).

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.

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