(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine hydrochloride

CAS Number: 171482-05-6
Category: Aprepitant Intermediates
Synonyms: (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine hydrochloride
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number171482-05-6
Molecular FormulaC20H19ClF7NO2
Molecular Weight473.81
Purity≥99.0%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
PackageFrom 100g/bottle to 25kg/drum

Product Overview

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine hydrochloride (CAS: 171482-05-6) is a chiral morpholine intermediate and key structural precursor in pharmaceutical synthesis.

Applications

Serves as the core advanced intermediate in the synthesis of neurokinin-1 (NK1) receptor antagonists, primarily Aprepitant and its prodrug Fosaprepitant dimeglumine.

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.