Methyl 2-(2-chloro-1-iminoethyl)hydrazinecarboxylate

CAS Number: 155742-64-6
Category: Aprepitant Intermediates
Synonyms: N-Methylcarbonyl-2-chloroacetamidrazone, Methyl (2Z)-2-(1-amino-2-chloroethylidene)hydrazinecarboxylate, N-Methoxycarbonyl-2-chloroacetamidrazone
✓ GMP-compliant ✓ Commercial supply&ample stock ✓ Various Packaging Available ✓ Factory documentation support

Product Specifications

CAS Number155742-64-6
Molecular FormulaC4H8ClN3O2
Molecular Weight165.58
Purity≥99.0%
AppearanceWhite to off-white solid
Storage Conditions2-8°C
PackageFrom 100g/bottle to 25kg/drum

Product Overview

Methyl 2-(2-chloro-1-iminoethyl)hydrazinecarboxylate (CAS: 155742-64-6) is a key functionalized hydrazinecarboxylate intermediate.

Applications

Serves as a key coupling building block and intermediate in the synthesis of neurokinin-1 (NK1) receptor antagonists, primarily used in the preparation of Aprepitant and Fosaprepitant (often utilized in cyclization steps to form the triazolinone ring).

Quality Assurance

Can be tested according to the customer’s method of analysis.

Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.