3-Acetamidophthalic anhydride
CAS Number: 287930-75-0
Category:
Aprepitant Intermediates
Synonyms: (R)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)morpholin-3-one
GMP-compliant
Commercial supply&le stock
Various Packaging Available
Factory documentation support
Product Specifications
| CAS Number | 287930-75-0 |
|---|---|
| Molecular Formula | C21H19F6NO3 |
| Molecular Weight | 447.38 |
| Purity | ≥99.0% |
| Appearance | White to off-white solid |
| Storage Conditions | 2-8°C |
| Package | From 100g/bottle to 25kg/drum |
Product Overview
3-Acetamidophthalic anhydride (CAS: 287930-75-0) is a substituted phthalic anhydride derivative widely used as a key building block and intermediate in organic synthesis and pharmaceutical manufacturing.
Applications
Serves as a key coupling partner in the synthesis of active pharmaceutical ingredients (APIs), most notably in the preparation of the PDE4 inhibitor Apremilast (Otezla) via condensation with 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine.
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
