5-(Chloromethyl)-1,2-dihydro-3H-1,2,4-triazol-3-one
CAS Number: 252742-72-6
Category:
Aprepitant Intermediates
Synonyms: 3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one, 5-(Chloromethyl)-2,4-dihydro-[1,2,4]triazol-3-one
GMP-compliant
Commercial supply&le stock
Various Packaging Available
Factory documentation support
Product Specifications
| CAS Number | 252742-72-6 |
|---|---|
| Molecular Formula | C3H4ClN3O |
| Molecular Weight | 133.54 |
| Purity | 98% |
| Appearance | White to off-white solid |
| Storage Conditions | Room Temperature |
| Package | From 100g/bottle to 25kg/drum |
Product Overview
5-(Chloromethyl)-1,2-dihydro-3H-1,2,4-triazol-3-one (CAS: 252742-72-6) is a functionalized heterocyclic building block and organic intermediate.
Applications
Pharmaceutical Intermediate: Serves as a key coupling agent and intermediate in the synthesis of neurokinin-1 (NK1) receptor antagonists, most notably used in the preparation of antiemetics such as Aprepitant and Fosaprepitant.
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
