(S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethanol
CAS Number: 225920-05-8
Category:
Aprepitant Intermediates
Synonyms: (S)-3,5-Bis(trifluoromethyl)-$\alpha$-methylbenzyl alcohol, (S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethan-1-ol
GMP-compliant
Commercial supply&le stock
Various Packaging Available
Factory documentation support
Product Specifications
| CAS Number | 225920-05-8 |
|---|---|
| Molecular Formula | C10H8F6O |
| Molecular Weight | 258.16 |
| Purity | ≥99.0% |
| Appearance | White to off-white solid |
| Storage Conditions | Room Temperature |
| Package | From 100g/bottle to 25kg/drum |
Product Overview
(S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol (CAS: 225920-05-8) is a chiral aromatic alcohol widely used as a key building block and intermediate in organic synthesis and pharmaceutical manufacturing.
Applications
Pharmaceutical Intermediate: Serves as an essential chiral precursor in the preparation of neurokinin-1 (NK1) receptor antagonists used as antiemetics, most notably Aprepitant, Fosaprepitant, and Rolapitant.
Chiral Synthesis: Used as a chiral auxiliary/building block for introducing the (S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy motif into biologically active compounds.
Quality Assurance
Can be tested according to the customer’s method of analysis.
Certificate of Analysis (COA) and Material Safety Data Sheets (MSDS) provided upon request.
